A retrospective evaluation of acute kidney injury and effects of renal replacement therapy in septic or nonseptic critically ILL patients
نویسندگان
چکیده
Methods After obtaining approval from the Ethics Committee, patients who were admitted to ICU between 01.01.2010 30.06.2014 and requiring RRT in the management of AKI were enrolled. They were divided into septic shock group or nonseptic group. Glasgow coma score (GCS), vital signs, laboratory values, vasopressor or inotropic agents requirements at initiation, 12 and 24 hours of RRT were collected. APACHE II scores, 28 and 90 day mortality were also recorded. Staging of AKI was carried out based on KDIGO 2012 guidelines and RIFLE (Risk, Injury, Failure, Loss of kidney function and Endstage renal failure).
منابع مشابه
Septic acute kidney injury in critically ill patients: clinical characteristics and outcomes.
Sepsis is the most common cause of acute kidney injury (AKI) in critical illness, but there is limited information on septic AKI. A prospective, observational study of critically ill patients with septic and nonseptic AKI was performed from September 2000 to December 2001 at 54 hospitals in 23 countries. A total of 1753 patients were enrolled. Sepsis was considered the cause in 833 (47.5%); the...
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BACKGROUND One of the most dreaded complications of septic shock is acute kidney injury. It occurs in around 50% of patients, with a mortality rate of about 60% at 3 months. There is no consensus on the optimal time to initiate renal replacement therapy. Retrospective and observational studies suggest that early implementation of renal replacement therapy could improve the prognosis for these p...
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